Hello, I'm

Qian-Ze Zhu

PhD Candidate at Harvard University exploring nonequilibrium self-organization and molecular computing through statistical physics, differentiable simulation, and machine learning.

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Qian-Ze Zhu

About Me

I am a 5th-year PhD student in Applied Physics at Harvard University, studying how computation, learning, and organization emerge in complex systems far from equilibrium. I am fortunate to be advised by Prof. Michael P. Brenner.

My research combines statistical physics, differentiable simulation and machine learning to uncover fundamental limits and design principles governing self-assembly, information flow, and molecular computation.

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Research Interests

Exploring the boundaries between physics, computation, and biology

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Nonequilibrium Self-Organization

Exploring how nonequilibrium driving and energy dissipation can steer robust self-assembly through mechanisms such as proofreading, error correction, and state change, enabling high-yield assembly beyond equilibrium limits.

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Molecular Computing

Studying how computation can be embedded in molecular dynamics, where tailored interactions and nonequilibrium kinetics guide physical and biological systems toward solutions of hard combinatorial problems.

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Differentiable Simulation

Developing end-to-end differentiable molecular dynamics and stochastic simulations to enable inverse design and optimization of stochastic physical and biological systems, especially far from equilibrium.

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Computational Biology

Modeling biological information processing, from gene regulatory networks to neural systems, using stochastic and physics-based computational frameworks.

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AI for Science

Developing AI systems that leverage large language models and search to automate scientific modeling, accelerate discovery, and build generalizable computational tools for physics and biology.